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Rapamycin and Dietary Restriction Induce Metabolically Distinctive Changes in Mouse Liver

Dietary restriction (DR) is the gold standard intervention used to delay aging, and much recent research has focused on the identification of possible DR mimetics. Energy sensing pathways, including insulin/IGF1 signaling, sirtuins, and mammalian Target of Rapamycin (mTOR), have been proposed as pat...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Yu, Zhen, Wang, Rong, Fok, Wilson C., Coles, Alexander, Salmon, Adam B., Pérez, Viviana I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447794/
https://ncbi.nlm.nih.gov/pubmed/24755936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu053
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