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Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction

It is well known that in mice the extension in lifespan by rapamycin is sexually dimorphic, in that it has a larger effect in females than males. In a previous study we showed that in male C57BL6 mice, rapamycin had less profound effects in both gene expression and liver metabolites when compared to...

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Bibliografski detalji
Izdano u:Springerplus
Glavni autori: Yu, Zhen, Sunchu, Bharath, Fok, Wilson C, Alshaikh, Nahla, Pérez, Viviana I
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447730/
https://ncbi.nlm.nih.gov/pubmed/26034704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-0909-7
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