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Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction

Rapamycin, a drug that has been shown to increase lifespan in mice, inhibits the target of rapamycin (TOR) pathway, a major pathway that regulates cell growth and energy status. It has been hypothesized that rapamycin and dietary restriction (DR) extend lifespan through similar mechanisms/pathways....

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Detaylı Bibliyografya
Asıl Yazarlar: Fok, Wilson C., Livi, Carolina, Bokov, Alex, Yu, Zhen, Chen, Yidong, Richardson, Arlan, Pérez, Viviana I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167584/
https://ncbi.nlm.nih.gov/pubmed/25075714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.07.004
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