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Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction
Rapamycin, a drug that has been shown to increase lifespan in mice, inhibits the target of rapamycin (TOR) pathway, a major pathway that regulates cell growth and energy status. It has been hypothesized that rapamycin and dietary restriction (DR) extend lifespan through similar mechanisms/pathways....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167584/ https://ncbi.nlm.nih.gov/pubmed/25075714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.07.004 |
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