p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress

Cell cycle checkpoints ensure that proliferation occurs only under permissive conditions, but their role in linking nutrient availability to cell division is incompletely understood. Protein folding within the endoplasmic reticulum (ER) is exquisitely sensitive to energy supply and amino acid source...

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Detalhes bibliográficos
Main Authors: Thomas, Sally E., Malzer, Elke, Ordóñez, Adriana, Dalton, Lucy E., van ′t Wout, Emily F. A., Liniker, Elizabeth, Crowther, Damian C., Lomas, David A., Marciniak, Stefan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597802/
https://ncbi.nlm.nih.gov/pubmed/23341460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424655
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