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piRNAs initiate an epigenetic memory of non-self RNA in the C. elegans germline
Organisms exhibit a fascinating array of gene-silencing pathways, which have evolved in part, to confront invasive nucleic acids such as transposons and viruses. A key question raised by the existence of these pathways is how do they distinguish “self” from “non-self” nucleic acids? Evidence exists...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597741/ https://ncbi.nlm.nih.gov/pubmed/22738726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.015 |
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