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A Co-CRISPR Strategy for Efficient Genome Editing in Caenorhabditis elegans

Genome editing based on CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclease (Cas9) has been successfully applied in dozens of diverse plant and animal species, including the nematode Caenorhabditis elegans. The rapid life cycle and easy access to the ovary by micro...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Heesun, Ishidate, Takao, Ghanta, Krishna S., Seth, Meetu, Conte, Darryl, Shirayama, Masaki, Mello, Craig C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125384/
https://ncbi.nlm.nih.gov/pubmed/24879462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.166389
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