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The C. elegans CSR-1 Argonaute pathway counteracts epigenetic silencing to promote germline gene expression

Organisms can develop adaptive sequence-specific immunity by re-expressing pathogen-specific small RNAs that guide gene silencing. For example, the C. elegans PIWI-Argonaute/piRNA pathway recruits RNA-dependent RNA polymerase RdRP to foreign sequences to amplify a trans-generational small RNA-induce...

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書誌詳細
主要な著者: Seth, Meetu, Shirayama, Masaki, Gu, Weifeng, Ishidate, Takao, Conte, Darryl, Mello, Craig C.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954781/
https://ncbi.nlm.nih.gov/pubmed/24360782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.11.014
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