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The C. elegans CSR-1 Argonaute pathway counteracts epigenetic silencing to promote germline gene expression
Organisms can develop adaptive sequence-specific immunity by re-expressing pathogen-specific small RNAs that guide gene silencing. For example, the C. elegans PIWI-Argonaute/piRNA pathway recruits RNA-dependent RNA polymerase RdRP to foreign sequences to amplify a trans-generational small RNA-induce...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954781/ https://ncbi.nlm.nih.gov/pubmed/24360782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.11.014 |
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