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C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts
Piwi Argonautes and Piwi-interacting RNAs (piRNAs) mediate genome defense by targeting transposons. However, many piRNA species lack obvious sequence complementarity to transposons or other loci; only one C. elegans transposon is a known piRNA target. Here we show that, in mutants lacking the Piwi A...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410639/ https://ncbi.nlm.nih.gov/pubmed/22738724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.016 |
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