CapSeq and CIP-TAP map 5′ ends of Pol II transcripts and reveal capped-small RNAs as C. elegans piRNA precursors

Piwi-interacting (pi) RNAs are germline-expressed small RNAs linked to epigenetic programming. C. elegans piRNAs are thought to be transcribed as independent gene-like loci. To test this idea and to identify potential Transcription Start (TS) sites for piRNA precursors, we developed CapSeq, an effic...

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Hlavní autoři: Gu, Weifeng, Lee, Heng-Chi, Chaves, Daniel, Youngman, Elaine M, Pazour, Gregory J, Conte, Darryl, Mello, Craig C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581324/
https://ncbi.nlm.nih.gov/pubmed/23260138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.023
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