Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

In spite of the many developments in synthetic oligonucleotide (ON) chemistry and design, invasion into double-stranded DNA (DSI) under physiological salt and pH conditions remains a challenge. In this work, we provide a new ON tool based on locked nucleic acids (LNAs), designed for strand invasion...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Moreno, Pedro M. D., Geny, Sylvain, Pabon, Y. Vladimir, Bergquist, Helen, Zaghloul, Eman M., Rocha, Cristina S. J., Oprea, Iulian I., Bestas, Burcu, Andaloussi, Samir EL, Jørgensen, Per T., Pedersen, Erik B., Lundin, Karin E., Zain, Rula, Wengel, Jesper, Smith, C. I. Edvard
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597675/
https://ncbi.nlm.nih.gov/pubmed/23345620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt007
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares