Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

In spite of the many developments in synthetic oligonucleotide (ON) chemistry and design, invasion into double-stranded DNA (DSI) under physiological salt and pH conditions remains a challenge. In this work, we provide a new ON tool based on locked nucleic acids (LNAs), designed for strand invasion...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Moreno, Pedro M. D., Geny, Sylvain, Pabon, Y. Vladimir, Bergquist, Helen, Zaghloul, Eman M., Rocha, Cristina S. J., Oprea, Iulian I., Bestas, Burcu, Andaloussi, Samir EL, Jørgensen, Per T., Pedersen, Erik B., Lundin, Karin E., Zain, Rula, Wengel, Jesper, Smith, C. I. Edvard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597675/
https://ncbi.nlm.nih.gov/pubmed/23345620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt007
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller