Endothelial NOS (NOS3) impairs myocardial function in developing sepsis

Endothelial nitric oxide synthase (NOS)3-derived nitric oxide (NO) modulates inotropic response and diastolic interval for optimal cardiac performance under non-inflammatory conditions. In sepsis, excessive NO production plays a key role in severe hypotension and myocardial dysfunction. We aimed to...

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Détails bibliographiques
Auteurs principaux: van de Sandt, Annette M., Windler, Rainer, Gödecke, Axel, Ohlig, Jan, Zander, Simone, Reinartz, Michael, Graf, Jürgen, van Faassen, Ernst E., Rassaf, Tienush, Schrader, Jürgen, Kelm, Malte, Merx, Marc W.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2013
Sujets:
Original Contribution
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597270/
https://ncbi.nlm.nih.gov/pubmed/23397596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0330-8
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