Endothelial NOS (NOS3) impairs myocardial function in developing sepsis

Endothelial nitric oxide synthase (NOS)3-derived nitric oxide (NO) modulates inotropic response and diastolic interval for optimal cardiac performance under non-inflammatory conditions. In sepsis, excessive NO production plays a key role in severe hypotension and myocardial dysfunction. We aimed to...

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Detalhes bibliográficos
Main Authors: van de Sandt, Annette M., Windler, Rainer, Gödecke, Axel, Ohlig, Jan, Zander, Simone, Reinartz, Michael, Graf, Jürgen, van Faassen, Ernst E., Rassaf, Tienush, Schrader, Jürgen, Kelm, Malte, Merx, Marc W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597270/
https://ncbi.nlm.nih.gov/pubmed/23397596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0330-8
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