Endothelial NOS (NOS3) impairs myocardial function in developing sepsis

Endothelial nitric oxide synthase (NOS)3-derived nitric oxide (NO) modulates inotropic response and diastolic interval for optimal cardiac performance under non-inflammatory conditions. In sepsis, excessive NO production plays a key role in severe hypotension and myocardial dysfunction. We aimed to...

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Main Authors: van de Sandt, Annette M., Windler, Rainer, Gödecke, Axel, Ohlig, Jan, Zander, Simone, Reinartz, Michael, Graf, Jürgen, van Faassen, Ernst E., Rassaf, Tienush, Schrader, Jürgen, Kelm, Malte, Merx, Marc W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer-Verlag 2013
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Original Contribution
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597270/
https://ncbi.nlm.nih.gov/pubmed/23397596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0330-8
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