Depletion of circulating blood NOS3 increases severity of myocardial infarction and left ventricular dysfunction

Nitric oxide (NO) derived from endothelial NO synthase (NOS3) plays a central role in myocardial ischemia/reperfusion (I/R)-injury. Subsets of circulating blood cells, including red blood cells (RBCs), carry a NOS3 and contribute to blood pressure regulation and RBC nitrite/nitrate formation. We hyp...

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Main Authors: Merx, Marc W., Gorressen, Simone, van de Sandt, Annette M., Cortese-Krott, Miriam M., Ohlig, Jan, Stern, Manuel, Rassaf, Tienush, Gödecke, Axel, Gladwin, Mark T., Kelm, Malte
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898535/
https://ncbi.nlm.nih.gov/pubmed/24346018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0398-1
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