Circulating Blood eNOS Contributes to the Regulation of Systemic Blood Pressure and Nitrite Homeostasis

OBJECTIVE: Mice genetically deficient in endothelial nitric oxide synthase (eNOS(−/−)) are hypertensive with lower circulating nitrite levels, indicating the importance of constitutively produced nitric oxide (NO•) to blood pressure regulation and vascular homeostasis. While the current paradigm hol...

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Autores principales: Wood, Katherine C., Cortese-Krott, Miriam M., Kovacic, Jason C., Noguchi, Audrey, Liu, Virginia B., Wang, Xunde, Raghavachari, Nalini, Boehm, Manfred, Kato, Gregory J., Kelm, Malte, Gladwin, Mark T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864011/
https://ncbi.nlm.nih.gov/pubmed/23702660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301068
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