53BP1 facilitates long-range DNA end-joining during V(D)J recombination

V(D)J recombination and class switch recombination employ overlapping but distinct non-homologous end-joining (NHEJ) pathways to repair DNA double strand break (DSB) intermediates. 53BP1 is a DNA damage response protein that is rapidly recruited to sites of chromosomal DSBs, where it appears to func...

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Autori principali: Difilippantonio, Simone, Gapud, Eric, Wong, Nancy, Huang, Ching-Yu, Mahowald, Grace, Chen, Hua Tang, Kruhlak, Michael J., Livak, Ferenc, Nussenzweig, Michel, Sleckman, Barry P., Nussenzweig, André
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596817/
https://ncbi.nlm.nih.gov/pubmed/18931658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07476
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