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Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α()

Iptakalim is a new ATP-sensitive potassium (K(ATP)) channel opener, and it inhibits the proliferation of pulmonary arterial smooth muscle cells (PASMCs) and pulmonary vascular remodeling. However, the underlying mechanism remains unclear. In the present study, we found that iptakalim significantly d...

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Bibliografische gegevens
Hoofdauteurs: Zuo, Xiangrong, Zong, Feng, Wang, Hui, Wang, Qiang, Xie, Weiping, Wang, Hong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Editorial Department of Journal of Biomedical Research 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596718/
https://ncbi.nlm.nih.gov/pubmed/23554716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(11)60052-3
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