The novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function

AIM: To investigate the effects of iptakalim on endothelial dysfunction induced by insulin resistance (IR) and to determine whether iptakalim improved IR associated with hypertension in fructose-fed rats (FFRs) and spontaneously hypertensive rats (SHRs). METHODS: Human umbilical vein endothelial cel...

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Detalhes bibliográficos
Main Authors: Wang, Yu, Zeng, Fu-hu, Long, Chao-liang, Pan, Zhi-yuan, Cui, Wen-yu, Wang, Ru-huan, Liu, Guo-shu, Wang, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010207/
https://ncbi.nlm.nih.gov/pubmed/22056616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.129
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