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The new antihypertensive drug iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels
AIM: To investigate the mechanisms underlying the activation of ATP-sensitive potassium channels (K(ATP)) by iptakalim in cultured rat mesenteric microvascular endothelial cells (MVECs). METHODS: Whole-cell K(ATP) currents were recorded in MVECs using automated patch clamp devices. Nucleotides (ATP,...
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| Опубликовано в: : | Acta Pharmacol Sin |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816240/ https://ncbi.nlm.nih.gov/pubmed/26592519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.97 |
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