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Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α()
Iptakalim is a new ATP-sensitive potassium (K(ATP)) channel opener, and it inhibits the proliferation of pulmonary arterial smooth muscle cells (PASMCs) and pulmonary vascular remodeling. However, the underlying mechanism remains unclear. In the present study, we found that iptakalim significantly d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Editorial Department of Journal of Biomedical Research
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596718/ https://ncbi.nlm.nih.gov/pubmed/23554716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(11)60052-3 |
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