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Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α()

Iptakalim is a new ATP-sensitive potassium (K(ATP)) channel opener, and it inhibits the proliferation of pulmonary arterial smooth muscle cells (PASMCs) and pulmonary vascular remodeling. However, the underlying mechanism remains unclear. In the present study, we found that iptakalim significantly d...

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Bibliografiske detaljer
Main Authors: Zuo, Xiangrong, Zong, Feng, Wang, Hui, Wang, Qiang, Xie, Weiping, Wang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Department of Journal of Biomedical Research 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596718/
https://ncbi.nlm.nih.gov/pubmed/23554716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(11)60052-3
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