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Iptakalim, an ATP-sensitive potassium channel opener, confers neuroprotection against cerebral ischemia/reperfusion injury in rats by protecting neurovascular unit cells

Objective: To investigate the role of iptakalim, an ATP-sensitive potassium channel opener, in transient cerebral ischemia/reperfusion (I/R) injury and its involved mechanisms. Methods: Intraluminal occlusion of middle cerebral artery (MCAO) in a rat model was used to investigate the effect of iptak...

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Bibliographic Details
Main Authors: Ran, Yu-hua, Wang, Hai
Format: Artigo
Language:Inglês
Published: Zhejiang University Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190099/
https://ncbi.nlm.nih.gov/pubmed/21960347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1100067
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