Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation

BACKGROUND AND PURPOSE: To evaluate the ability of cannabidiolic acid (CBDA) to reduce nausea and vomiting and enhance 5-HT(1A) receptor activation in animal models. EXPERIMENTAL APPROACH: We investigated the effect of CBDA on (i) lithium chloride (LiCl)-induced conditioned gaping to a flavour (naus...

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Detalhes bibliográficos
Main Authors: Bolognini, D, Rock, EM, Cluny, NL, Cascio, MG, Limebeer, CL, Duncan, M, Stott, CG, Javid, FA, Parker, LA, Pertwee, RG
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596650/
https://ncbi.nlm.nih.gov/pubmed/23121618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12043
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