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Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus

BACKGROUND AND PURPOSE: We evaluated the anti-emetic and anti-nausea properties of the acid precursor of Δ(9)-tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), and determined its mechanism of action in these animal models. EXPERIMENTAL APPROACH: We investigated the effect of THCA on li...

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Detalhes bibliográficos
Main Authors: Rock, E M, Kopstick, R L, Limebeer, C L, Parker, L A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792001/
https://ncbi.nlm.nih.gov/pubmed/23889598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12316
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