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A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis
The p53 tumor suppressor responds to certain cellular stresses by inducing transcriptional programs that can lead to growth arrest or apoptosis. However, the molecular mechanisms responsible for choosing between these two cell fates are not well understood. Previous studies have suggested that p53 s...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595483/ https://ncbi.nlm.nih.gov/pubmed/23306555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.155 |
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