Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts.
Treatment of intact Rat-1 fibroblasts with epidermal growth factor (EGF) leads to rapid activation of cellular ras-encoded proteins. By using the bacterial toxin streptolysin O to permeabilize these cells, it was shown that the low basal rate at which guanine nucleotides bind to, and dissociate from...
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| Publicado en: | Mol Cell Biol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1993
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1903-1910.1993 |
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