Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras.

Shc proteins are phosphorylated on tyrosine residues and associate with growth factor receptor-bound protein 2 (Grb2) upon treatment of cells with epidermal growth factor (EGF) or insulin. We have studied the role of Shc in insulin- and EGF-induced activation of p21ras in NIH 3T3 cells overexpressin...

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Hlavní autoři: Pronk, G J, de Vries-Smits, A M, Buday, L, Downward, J, Maassen, J A, Medema, R H, Bos, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC358516/
https://ncbi.nlm.nih.gov/pubmed/8114695
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