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Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras.

Shc proteins are phosphorylated on tyrosine residues and associate with growth factor receptor-bound protein 2 (Grb2) upon treatment of cells with epidermal growth factor (EGF) or insulin. We have studied the role of Shc in insulin- and EGF-induced activation of p21ras in NIH 3T3 cells overexpressin...

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Udgivet i:Mol Cell Biol
Principais autores: Pronk, G J, de Vries-Smits, A M, Buday, L, Downward, J, Maassen, J A, Medema, R H, Bos, J L
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8114695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.3.1575-1581.1994
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