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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras.

Conversion of Ras proteins into an activated GTP-bound state able to bind effector proteins is catalyzed by specific guanine nucleotide exchange factors in response to a large number of extracellular stimuli. Here we report the isolation of mouse cDNAs encoding Ras-GRF2, a multidomain 135-kDa protei...

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Publicat a:Mol Cell Biol
Autors principals: Fam, N P, Fan, W T, Wang, Z, Zhang, L J, Chen, H, Moran, M F
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032266/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1396
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