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Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts.
Treatment of intact Rat-1 fibroblasts with epidermal growth factor (EGF) leads to rapid activation of cellular ras-encoded proteins. By using the bacterial toxin streptolysin O to permeabilize these cells, it was shown that the low basal rate at which guanine nucleotides bind to, and dissociate from...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1993
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1903 |
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