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Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis
Completion of DNA replication needs to be ensured even when challenged with fork progression problems or DNA damage. PCNA and its modifications constitute a molecular switch to control distinct repair pathways. In yeast, SUMOylated PCNA (S-PCNA) recruits Srs2 to sites of replication where Srs2 can d...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
European Molecular Biology Organization
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594751/ https://ncbi.nlm.nih.gov/pubmed/23395907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.9 |
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