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Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1
Cyclins E1 drives the initiation of DNA replication, and deregulation of its periodic expression leads to mitotic delay associated with genomic instability. Since it is not known whether the closely related protein cyclin E2 shares these properties, we overexpressed cyclin E2 in breast cancer cells....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594261/ https://ncbi.nlm.nih.gov/pubmed/23324395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23512 |
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