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4-Hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPARγ and accelerating ubiquitin–proteasome degradation

Although well-established, the underlying mechanisms involved in obesity-related plasma adiponectin decline remain elusive. Oxidative stress is associated with obesity and insulin resistance and considered to contribute to the progression toward obesity-related metabolic disorders. In this study, we...

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Bibliografski detalji
Glavni autori: Wanga, Zhigang, Dou, Xiaobing, Gu, Dongfang, Shen, Chen, Yao, Tong, Nguyen, Van, Braunschweig, Carol, Song, Zhenyuan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594100/
https://ncbi.nlm.nih.gov/pubmed/22085560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.10.027
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