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eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

Recognition of the methyl-7-guanosine (m(7)G) cap structure on mRNA is an essential feature of mRNA metabolism and thus gene expression. Eukaryotic translation initiation factor 4E (eIF4E) promotes translation, mRNA export, proliferation, and oncogenic transformation dependent on this cap-binding ac...

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Bibliografiske detaljer
Main Authors: Osborne, Michael J., Volpon, Laurent, Kornblatt, Jack A., Culjkovic-Kraljacic, Biljana, Baguet, Aurélie, Borden, Katherine L. B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593863/
https://ncbi.nlm.nih.gov/pubmed/23431134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216862110
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