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eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

Recognition of the methyl-7-guanosine (m(7)G) cap structure on mRNA is an essential feature of mRNA metabolism and thus gene expression. Eukaryotic translation initiation factor 4E (eIF4E) promotes translation, mRNA export, proliferation, and oncogenic transformation dependent on this cap-binding ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Osborne, Michael J., Volpon, Laurent, Kornblatt, Jack A., Culjkovic-Kraljacic, Biljana, Baguet, Aurélie, Borden, Katherine L. B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593863/
https://ncbi.nlm.nih.gov/pubmed/23431134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216862110
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