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Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics
CO(2) is produced abundantly by cardiac mitochondria. Thus an efficient means for its venting is required to support metabolism. Carbonic anhydrase (CA) enzymes, expressed at various sites in ventricular myocytes, may affect mitochondrial CO(2) clearance by catalyzing CO(2) hydration (to H(+) and HC...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593844/ https://ncbi.nlm.nih.gov/pubmed/23431149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213471110 |
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