Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Monocytes regulate host defenses, inflammation, and tissue homeostasis. The transcription factor interferon regulatory factor-8 (IRF8) stimulates monocyte/macrophage differentiation, yet genome-wide understanding of the differentiation program initiated by IRF8 is lacking. By combining chromatin imm...

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Bibliographische Detailangaben
Hauptverfasser: Kurotaki, Daisuke, Osato, Naoki, Nishiyama, Akira, Yamamoto, Michio, Ban, Tatsuma, Sato, Hideaki, Nakabayashi, Jun, Umehara, Marina, Miyake, Noriko, Matsumoto, Naomichi, Nakazawa, Masatoshi, Ozato, Keiko, Tamura, Tomohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591803/
https://ncbi.nlm.nih.gov/pubmed/23319570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-437863
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