Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

Basophils and mast cells play critical roles in host defense against pathogens and allergic disorders. However, the molecular mechanism by which these cells are generated is not completely understood. Here we demonstrate that interferon regulatory factor-8 (IRF8), a transcription factor essential fo...

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Veröffentlicht in:Blood
Hauptverfasser: Sasaki, Haruka, Kurotaki, Daisuke, Osato, Naoki, Sato, Hideaki, Sasaki, Izumi, Koizumi, Shin-ichi, Wang, Hongsheng, Kaneda, Chika, Nishiyama, Akira, Kaisho, Tsuneyasu, Aburatani, Hiroyuki, Morse, Herbert C., Ozato, Keiko, Tamura, Tomohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287642/
https://ncbi.nlm.nih.gov/pubmed/25398936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-557983
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