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Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

Basophils and mast cells play critical roles in host defense against pathogens and allergic disorders. However, the molecular mechanism by which these cells are generated is not completely understood. Here we demonstrate that interferon regulatory factor-8 (IRF8), a transcription factor essential fo...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Sasaki, Haruka, Kurotaki, Daisuke, Osato, Naoki, Sato, Hideaki, Sasaki, Izumi, Koizumi, Shin-ichi, Wang, Hongsheng, Kaneda, Chika, Nishiyama, Akira, Kaisho, Tsuneyasu, Aburatani, Hiroyuki, Morse, Herbert C., Ozato, Keiko, Tamura, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287642/
https://ncbi.nlm.nih.gov/pubmed/25398936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-557983
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