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The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse
Among dendritic cell (DC) subsets, CD8α(+) DCs and plasmacytoid DCs (pDCs) produce high levels of IL12 and type I interferons (IFNs), respectively, and confer early innate immunity. Development of CD8α(+) DCs and pDCs requires the interferon regulatory factor 8 (IRF8). Recently, a spontaneous point...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234043/ https://ncbi.nlm.nih.gov/pubmed/18055870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-100750 |
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