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Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice

Dendritic cells (DCs), which are vital for immune responses, are derived from bone marrow hematopoietic stem cells via common DC progenitors (CDPs). DC lineage fate decisions occurring at stages much earlier than CDPs have recently been recognized, yet the mechanism remains elusive. By single-cell R...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kurotaki, Daisuke, Kawase, Wataru, Sasaki, Haruka, Nakabayashi, Jun, Nishiyama, Akira, Morse, Herbert C., Ozato, Keiko, Suzuki, Yutaka, Tamura, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484390/
https://ncbi.nlm.nih.gov/pubmed/30796024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-857789
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