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Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice

Dendritic cells (DCs), which are vital for immune responses, are derived from bone marrow hematopoietic stem cells via common DC progenitors (CDPs). DC lineage fate decisions occurring at stages much earlier than CDPs have recently been recognized, yet the mechanism remains elusive. By single-cell R...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Kurotaki, Daisuke, Kawase, Wataru, Sasaki, Haruka, Nakabayashi, Jun, Nishiyama, Akira, Morse, Herbert C., Ozato, Keiko, Suzuki, Yutaka, Tamura, Tomohiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484390/
https://ncbi.nlm.nih.gov/pubmed/30796024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-857789
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