Architecture and Assembly of HIV Integrase Multimers in the Absence of DNA Substrates

We have applied small angle x-ray scattering and protein cross-linking coupled with mass spectrometry to determine the architectures of full-length HIV integrase (IN) dimers in solution. By blocking interactions that stabilize either a core-core domain interface or N-terminal domain intermolecular c...

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Detaylı Bibliyografya
Asıl Yazarlar: Bojja, Ravi Shankar, Andrake, Mark D., Merkel, George, Weigand, Steven, Dunbrack, Roland L., Skalka, Anna Marie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591645/
https://ncbi.nlm.nih.gov/pubmed/23322775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434431
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