The conformational feasibility for the formation of reaching dimer in ASV and HIV Integrase: a molecular dynamics study

Retroviral integrases are reported to form alternate dimer assemblies like the core-core dimer and reaching dimer. The core-core dimer is stabilized predominantly by an extensive interface between two catalytic core domains. The reaching dimer is stabilized by N-terminal domains (NTD) that reach to...

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Détails bibliographiques
Publié dans:J Biomol Struct Dyn
Auteurs principaux: Balasubramanian, Sangeetha, Rajagopalan, Muthukumaran, Bojja, Ravi Shankar, Skalka, Anna Marie, Andrake, Mark D., Ramaswamy, Amutha
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570655/
https://ncbi.nlm.nih.gov/pubmed/27835934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2016.1257955
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