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Binding Interactions with the Complementary Subunit of Nicotinic Receptors

The agonist-binding site of nicotinic acetylcholine receptors (nAChRs) spans an interface between two subunits of the pentameric receptor. The principal component of this binding site is contributed by an α subunit, and it binds the cationic moiety of the nicotinic pharmacophore. The other part of t...

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Detalhes bibliográficos
Main Authors: Blum, Angela P., Van Arnam, Ethan B., German, Laurel A., Lester, Henry A., Dougherty, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591609/
https://ncbi.nlm.nih.gov/pubmed/23349463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.439968
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