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Evidence for an Extended Hydrogen Bond Network in the Binding Site of the Nicotinic Receptor: ROLE OF THE VICINAL DISULFIDE OF THE α1 SUBUNIT
The defining feature of the α subunits of the family of nicotinic acetylcholine receptors is a vicinal disulfide between Cys-192 and Cys-193. Although this structure has played a pivotal role in a number of pioneering studies of nicotinic receptors, its functional role in native receptors remains un...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173184/ https://ncbi.nlm.nih.gov/pubmed/21757705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254235 |
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