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An Intersubunit Hydrogen Bond in the Nicotinic Acetylcholine Receptor That Contributes to Channel Gating

The muscle nicotinic acetylcholine receptor is a large, allosteric, ligand-gated ion channel with the subunit composition α(2)βγδ. Although much is now known about the structure of the binding site, relatively little is understood about how the binding event is communicated to the channel gate, caus...

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Detalhes bibliográficos
Main Authors: Gleitsman, Kristin Rule, Kedrowski, Sean M. A., Lester, Henry A., Dougherty, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602911/
https://ncbi.nlm.nih.gov/pubmed/18952603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807226200
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