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Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors

Designing subtype-selective agonists for neuronal nicotinic acetylcholine receptors is a challenging and significant goal aided by intricate knowledge of each subtype’s binding patterns. We previously reported that in α6β2 receptors, acetylcholine makes a functional cation-π interaction with Trp149,...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biochemistry
Päätekijät: Post, Michael R., Lester, Henry A., Dougherty, Dennis A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075822/
https://ncbi.nlm.nih.gov/pubmed/28287260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00213
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