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Two Neuronal Nicotinic Acetylcholine Receptors, α4β4 and α7, Show Differential Agonist Binding Modes

Nicotinic acetylcholine receptors (nAChRs) are pentameric, neurotransmitter-gated ion channels responsible for rapid excitatory neurotransmission in the central and peripheral nervous systems, resulting in skeletal muscle tone and various cognitive effects in the brain. These complex proteins are ac...

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Hlavní autoři: Puskar, Nyssa L., Xiu, Xinan, Lester, Henry A., Dougherty, Dennis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077659/
https://ncbi.nlm.nih.gov/pubmed/21343288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206565
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