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Evidence for an Extended Hydrogen Bond Network in the Binding Site of the Nicotinic Receptor: ROLE OF THE VICINAL DISULFIDE OF THE α1 SUBUNIT

The defining feature of the α subunits of the family of nicotinic acetylcholine receptors is a vicinal disulfide between Cys-192 and Cys-193. Although this structure has played a pivotal role in a number of pioneering studies of nicotinic receptors, its functional role in native receptors remains un...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blum, Angela P., Gleitsman, Kristin Rule, Lester, Henry A., Dougherty, Dennis A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173184/
https://ncbi.nlm.nih.gov/pubmed/21757705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254235
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