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Analysis of the Membrane Proteome of Ciprofloxacin-Resistant Macrophages by Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)

Overexpression of multidrug transporters is a well-established mechanism of resistance to chemotherapy, but other changes may be co-selected upon exposure to drugs that contribute to resistance. Using a model of J774 macrophages made resistant to the fluoroquinolone antibiotic ciprofloxacin and comp...

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Detalhes bibliográficos
Main Authors: Caceres, Nancy E., Aerts, Maarten, Marquez, Béatrice, Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M., Devreese, Bart, Van Bambeke, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591400/
https://ncbi.nlm.nih.gov/pubmed/23505477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058285
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