Cellular Accumulation and Activity of Quinolones in Ciprofloxacin-Resistant J774 Macrophages

Ciprofloxacin is the substrate for a multidrug resistance-related protein (MRP)-like multidrug transporter in J774 mouse macrophages, which also modestly affects levofloxacin but only marginally affects garenoxacin and moxifloxacin (J.-M. Michot et al., Antimicrob. Agents Chemother. 49:2429-2437, 20...

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Main Authors: Michot, Jean-Michel, Heremans, Marie F., Caceres, Nancy E., Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M., Van Bambeke, Françoise
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472235/
https://ncbi.nlm.nih.gov/pubmed/16641436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1689-1695.2006
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